Summary: Celebrex is one of the brand names of Celecoxib, a drug manufactured and marketed by Pfizer. It is available as capsules and the risks associated include heart disease and gastrointestinal adverse effects. Research is also being conducted into cancer prevention using Celebrex.

Celebrex, also known as Celecoxib or Celebra, is a selective COX-2 inhibitor and a sulfa non-steroidal anti-inflammatory drug (NSAID). It is available in the form of capsules manufactured by Pfizer and is available only by prescription. The uses of the drug include to lessen the number of rectal and polyps in patients suffering from familial adenomatous polyposis, treatment of acute pain, rheumatoid arthritis, osteoarthritis, treatment of pains during menstruation and ankylosing spondylitis. Prior to celebrex, conventional NSAIDs would cause adverse gastrointestinal effects and Celebrez was developed as an alternative that can cure acute pain without the adverse effects. But it is only used in cases where patients have to use for a long term period to cure acute pain, otherwise conventional NSAIDS are used because the gastrointestinal effects won’t be so pronounced with a couple of times of consumption.

There were claims that the efficacy of the drug has been fabricated but Pfizer has shot down the claims; and the drug has long since been FDA approved. The drug is available in dosages of 400 mg, 200 mg, 100 mg and 50 mg. It being a new drug, is covered by patents in the United States and cannot be sold as a generic drug for the remainder of the 20 year period that drug holds the patent. But generic versions are available legally in eastern countries including India, Philippines, and Vietnam. Recommended dosage of Celebrex is no more that 200 mg per day. The lowest possible dosage should be used in order to minimize the adverse effects.

Speaking of adverse effects, keep in mind that the gastrointestinal adverse effects are not completely eliminated, they are just reduced. So patients with a prior history of gastrointestinal bleeding should be especially careful as gastrointestinal toxicity can occur. There is a chance of allergy for those who are allergic to sulfonamide drugs as celebrex has a sulfonamide moiety. And regarding pregnancy, it is a pregnancy category C drug. And there is an increase chance of heart attack and stroke in people using NSAID drugs. FDA requires Celebrex to carry a black box warning about the risk of gastrointestinal and cardiovascular side effects.

Some of the investigative uses of celebrex include cancer prevention as it has been suggested that chance of certain cancers might be reduced significantly. Bu then again, the risk of heart disease and stroke means it is not recommended for preventive use.

Summary: Ultracet is one of the brand names of Tramadol – a centrally acting opioid painkiller used to treat moderate to severe pain. The drug is primary a painkiller, but it has its share of side effects. There is potential for abuse of the drug and a doctor’s prescription is necessary.

Ultracet, also known as Ultram and Tramal, is the brand name of the drug Tramadol hydrochloride, simply known as Tramadol for the generic version. It is a painkiller primarily. It is a centrally acting opioid that can treat moderate to severe pain. Restless legs syndrome and fibromyalgia can be cured by Tramadol. The German drug firm Grünenthal GmbH has been manufacturing and marketing the drug for more than 40 years. The drug is a centrally acting opioid, meaning it acts on opiate receptors in the body. Respiratory depression and euphoria are the known side effects of Ultracet. The latter one is what is leading to the drug being abused. People can become addicted to it and hence its use is restricted and regulated as per FDA guidelines.

In its mechanism of action, Ultram has been compared to levarphenol and codeine and these can be considered alternatives. Physicians consider prescribing these if the patient has a history of addiction problems. Research is going on regarding use of Ultracet as a drug to cure anxiety, depression and phobias; but physicians usually don’t recommend this unless everything has failed. Intervention of a psychiatrist is necessary when Ultracet is used as an antidepressant. Some other investigative uses of Ultracet are for use against obsessive compulsive disorder, obsessive compulsive disorder, premature ejaculation, management of opiate withdrawal symptoms and diabetic neuropathy.

Ultracet should not be taken by pregnant women as it can cause death of the baby in extreme cases. The drug should not be taken by pregnant women unless the benefits significantly outweigh the risks. The drug can even pass into breast milk, so a suckling baby ends up ingesting it. Whatever a mother takes, the baby gets it. However, not much of a risk in this as the quantity taken in is too insignificant. As per FDA guidelines, the adverse effects of the drug have to be made clear in no uncertain terms. Side effects can include respiratory problems and it can be addictive. It is thus plagued by all the problems that addictive drugs are associated with like tolerance, dependence, withdrawal, etc.

The taste of Ultracet is bitter like all opioid drugs. Sometime, the taste is masked by sweeteners. There are many forms of the drug available as tablets, suppositories, intravenous, transdermal patch, liquid and capsule. Not more than 400 mg per day should be taken orally and for intravenous administration, the dosage is not to exceed 600 mg per day.

Summary: Ultram is a centrally acting opioid analgesic which is used to treat pain that can range from moderate to moderately severe and has also been useful in the treatment of fibromyalgia and restless legs syndrome. One should know about the effects and side effects of the drug before consuming it.

Know About Ultram

Ultram is well known trade name for Tramadol hydrochloride. It is a centrally acting opioid painkiller used to treat pain that ranged from moderate to severe. The drug is also used in the treatment of fibromyalgia and restless legs syndrome. It has been around for more than 40 years and is made and manufactured by the German drug company Grünenthal GmbH. Opioids act on the opiate receptors of the body and are hence considered and effects include respiratory depression and euphoria. The euphoria part leads people to abuse the drug. Ultram is somewhat similar to codeine and levarphenol. It has been suggested that Ultram can be used to treat depression, anxiety, and phobias, but its use is restricted to last resort use when everything else has failed and the treatment must be administered under psychiatric supervision.

The FDA has regulations on the makers of the drug and mandates them to state the adverse affects clearly, to mention that the drug can be addictive and those using it can suffer from respiratory problems. Tramadol cannot be used to gradually reduce dependency of patients on opiate drugs. Ultram is a central nervous system acting drug and is available in both oral and intravenous form. It is most commonly sold a 50 mg does by generic manufacturers. Some of the forms in which Tramadol is available are – tablets, capsules (ordinary and late acting), suppositories, effervescent powders and tablets, vials of sterile solution for injection, transdermal patch, spinal injection powders, liquids and in tablets mixed with other drugs like paracetamol, acetaminophen and aspirin.

The taste of Ultram is characteristically bitter and oral medication can come with or without masking flavors. The recommended dosage is not to exceed 400 mg for oral use and for parenteral, not more that 600 mg should be used. Ultram is available is doses of 100 mg, 200 mg and a maximum of 300 mg. Doctors should be consulted before consumption of this medicine. Some other uses of Ultram are being investigated into and its effectiveness against premature ejaculation, obsessive compulsive disorder, management of opiate withdrawal symptoms, postherpetic neuralgia and diabetic neuropathy.

Tramadol should not be taken during pregnancy as the risks involved are too great. It can even be fatalistic to babies. Lactating mothers should not take Tramadol as it can pass into breast milk, but the dosage is said to be too small to cause any harm. Nevertheless, avoid unless it is absolutely necessary.

Summary- Ultram is a pain-killing drug, whose generic name is Tramadol. This drug is consumed to ease pains caused due to cancer, arthritis, surgery, headache, etc. This medicine should always be consumed under the guidance of doctors to prevent serious side effects.

Ultram is a pain relief drug, which is used for treating moderate to severe pains. The generic name of this drug is Tramadol. According to research, its effects are similar to the effects of narcotics in the human body. However, it does not invite as many side effects as a narcotic drug would to the human body. Tramadol is effective in curing pain ranging from those that are caused by cancer to those of arthritis and even surgical pains. Sometimes it also helps to reduce severe headaches and endometriosis, which other drugs may fail to cure.

Tramadol is usually taken orally as directed by the physician. Besides the many advantages, there are certain side effects or ill effects, which this drug can cause as well mainly due to misuse. The first sign is the tendency of dependence on this drug. Certain types of withdrawal effects occur namely, mood disorders, sleeplessness, jitteriness, watering eyes, nausea, runny nose, sweating, muscle aches, etc., if the dose is stopped suddenly. Certain kinds of allergic reactions like, breathing difficulties, and swelling of face, lips, throat or tongue are serious side effects of Tramadol, which need emergency medical attention. People who are under the medication of Ultram are recommended not to drive or operate heavy machinery.

As long as you are using Ultram, it is advisable to go for regular checkups with the doctor and report if any signs of side effects crop up. Before starting to use Tramadol, have a detailed session with your doctor describing any king of medical history or drug dependencies you had in past or have presently, as that will help him to prescribe the right dosage for you. Tramadol is a petty powerful drug and while consuming it you have to be a bit conscious always. Any change in the dosage can cause serious side effects. Therefore, it is advisable to consult your doctor instead of changing the dosage of the medicine on your own.

Another word of warning that comes with the medicine is that, you ought to inform your physician if you are using alcohol or any other over the counter drug as they may trigger the side effects of Tramadol. Besides the side effects, this medicine can work wonders with any kind of pain, from moderate to severe. You just need to follow certain guidelines and instructions from your doctor and you can enjoy a pain free life with Tramadol.